Bald Thigh Syndrome

Gene: IGFBP5

Transmission: not determined

Mutation: Substitution, IGFBP5 gene

Medical system: dermal

Breeds: Afgan Hound, Azawakh, Belgian Malinois, Belgian Sheepdog, Bichon Frise, Biewer Terrier, Border Collie, Chihuahua, Curly-Coated Retriever, Dutch Shepherd, Flat-Coated Retriever, Greyhound, Italian Greyhound, Kromfohrlander, Lancashire Heeler, Lhasa Apso, Maltese Terrier, Papillon / Continental Toy Spaniel, Pomeranian, Rhodesian Ridgeback, Russell Terrier, Saluki, Schipperke, Scottish Deerhound, Shih Tzu, Staffordshire Bull Terrier, Whippet

References: 

OMIA link: [2168-9615]

Donner J, Freyer J, Davison S, et al. (2023) Genetic prevalence and clinical relevance of canine Mendelian disease variants in over one million dogs.  PLoS Genet. 19(2):e1010651. [pubmed/36848397]

Brunner MAT, Rüfenacht S, Bauer A, et al. (2019) Bald thigh syndrome in sighthounds-Revisiting the cause of a well-known disease.  PLoS One 14(2):e0212645.  [pubmed/30794648]